2021 U.S.-Booked Air Volume: $18 million 

Biopharmaceutical company AbbVie saw U.S.-booked air volume increase to $18 million in 2021, up from $11.3 million in 2020, according to BTN estimates. This reflects positive sales growth as the company reported net revenues of more than $56 billion for the year, an increase of nearly 23 percent from 2020, after the U.S. Food and Drug Administration approved new products and expanded indications for several medicines. 
Following the 2020 acquisition of fellow biopharmaceutical company Allergan, the company employed about 50,000 people worldwide in 2021.